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1

NITROXYL (HNO): Chemistry, Biochemistry, and Pharmacology

Fukuto, Jon M., Switzer, Christopher H., Miranda, Katrina M., Wink, David A.

Journal:

Annual Review of Pharmacology

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

2

Teaching Upper Division Chemistry and Biochemistry Capstone Lab Courses During a Pandemic

Works, Carmen, Fukuto, Jon, Lares, Monica, Negru, Bogdan, Lillig, Jennifer

Journal:

Journal of Chemical Education

Year:

2020

File:

PDF, 914 KB

2020

3

Carbon disulfide. Just toxic or also bioregulatory and/or therapeutic?

DeMartino, Anthony W., Zigler, David F., Fukuto, Jon M., Ford, Peter C.

Journal:

Chemical Society Reviews

Year:

2016

Language:

english

File:

PDF, 3.65 MB

english, 2016

4

Reactions of HNO with Heme Proteins: New Routes to HNO−Heme Complexes and Insight into Physiological Effects

Kumar, Murugaeson R., Fukuto, Jon M., Miranda, Katrina M., Farmer, Patrick J.

Journal:

Inorganic Chemistry

Year:

2010

Language:

english

File:

PDF, 2.70 MB

english, 2010

5

Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle

Louis J. Ignarro, Peggy A. Bush, Georgette M. Buga, Keith S. Wood, Jon M. Fukuto, Jacob Rajfer

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 517 KB

english, 1990

6

The Reaction of Hydrogen Sulfide with Disulfides: Formation of a Stable Trisulfide and Implications to Biological Systems

Bianco, Christopher L, Akaike, Takaaki, Ida, Tomoaki, Nagy, Peter, Bogdandi, Virag, Toscano, John P, Kumagai, Yoshito, Henderson, Catherine F, Goddu, Robert N, Lin, Joseph, Fukuto, Jon M

Journal:

British Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 724 KB

english, 2018

7

Comparing the chemical biology of NO and HNO

Wilmarie Flores-Santana, Christopher Switzer, Lisa A. Ridnour, Debashree Basudhar, Daniele Mancardi, Sonia Donzelli, Douglas D. Thomas, Katrina M. Miranda, Jon M. Fukuto, David A. Wink

Journal:

Archives of Pharmacal Research

Year:

2009

Language:

english

File:

PDF, 318 KB

english, 2009

8

Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide

Olson, Kenneth R., Gao, Yan, Arif, Faihaan, Patel, Shivali, Yuan, Xiaotong, Mannam, Varun, Howard, Scott, Batinic-Haberle, Ines, Fukuto, Jon, Minnion, Magdalena, Feelisch, Martin, Straub, Karl D.

Journal:

Year:

2019

File:

PDF, 2.10 MB

2019

9

[Advances in Pharmacology] Nitric Oxide - Biochemistry, Molecular Biology, and Therapeutic Implications Volume 34 || Chemistry of Nitric Oxide: Biologically Relevant Aspects

Year:

1995

Language:

english

File:

PDF, 785 KB

english, 1995

10

Nitroxyl inhibits breast tumor growth and angiogenesis

Andrew J. Norris, Maryam R. Sartippour, Ming Lu, Taylor Park, Jian Yu Rao, Matthew I. Jackson, Jon M. Fukuto, Mai N. Brooks

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 245 KB

english, 2008

11

The Role of Oxygen and Reduced Oxygen Species in Nitric Oxide-Mediated Cytotoxicity: Studies in the Yeast Saccharomyces cerevisiae Model System

Kenneth T. Chiang, Christopher H. Switzer, Kizito O. Akali, Jon M. Fukuto

Journal:

Toxicology and Applied Pharmacology

Year:

2000

Language:

english

File:

PDF, 93 KB

english, 2000

12

The emergence of nitroxyl (HNO) as a pharmacological agent

Christopher H. Switzer, Wilmarie Flores-Santana, Daniele Mancardi, Sonia Donzelli, Debashree Basudhar, Lisa A. Ridnour, Katrina M. Miranda, Jon M. Fukuto, Nazareno Paolocci, David A. Wink

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

13

Biological Activity of Designed Photolabile Metal Nitrosyls: Light-Dependent Activation of Soluble Guanylate Cyclase and Vasorelaxant Properties in Rat Aorta

Madhani, Melanie, Patra, Apurba K., Miller, Thomas W., Eroy-Reveles, Aura A., Hobbs, Adrian J., Fukuto, Jon M., Mascharak, Pradip K.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

14

Mechanisms of Nitrogen Oxide-Mediated Disruption of Metalloprotein Function: An Examination of the Copper-Responsive Yeast Transcription Factor Ace1

Shinyashiki, Masaru, Pan, Chuan-Ju G., Switzer, Christopher H., Fukuto, Jon M.

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

15

The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase α is mediated by hydrogen peroxide

Michael P. Bova, Matthew N. Mattson, Stefan Vasile, Danny Tam, Leslie Holsinger, Meire Bremer, Terence Hui, Gerald McMahon, Audie Rice, Jon M. Fukuto

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 308 KB

english, 2004

16

P067. Effect of changing redox status on the activation of soluble guanylate cyclase by nitrogen oxides

Thomas W. Miller, Nestor E. Franco, Adrian J. Hobbs, Louis J. Ignarro, Jon M. Fukuto

Journal:

Year:

2006

Language:

english

File:

PDF, 61 KB

english, 2006

17

Polyamine-Induced Rapid Root Abscission in Azolla pinnata

Gurung, Sushma, Cohen, Michael F., Fukuto, Jon, Yamasaki, Hideo

Journal:

Journal of Amino Acids

Year:

2012

Language:

english

File:

PDF, 1.99 MB

english, 2012

18

Interactive Endogenous Small Molecule (Gaseous) Signaling: Implications for Teratogenesis

Fukuto, Jon, Collins, Michael

Journal:

Current Pharmaceutical Design

Year:

2007

Language:

english

File:

PDF, 476 KB

english, 2007

19

The chemical biology of HNO signaling

Bianco, Christopher L., Toscano, John P., Bartberger, Michael D., Fukuto, Jon M.

Journal:

Archives of Biochemistry and Biophysics

Year:

2016

Language:

english

File:

PDF, 488 KB

english, 2016

20

Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm

Wink, David A., Miranda, Katrina M., Katori, Tatsuo, Mancardi, Daniele, Thomas, Douglas D., Ridnour, Lisa, Espey, Michael G., Feelisch, Martin, Colton, Carol A., Fukuto, Jon M., Pagliaro, Pasquale, Ka

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2003

Language:

english

File:

PDF, 229 KB

english, 2003

21

Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling?

Heppner, David E., Hristova, Milena, Ida, Tomoaki, Mijuskovic, Ana, Dustin, Christopher M., Bogdándi, Virág, Fukuto, Jon M., Dick, Tobias P., Nagy, Péter, Li, Jianing, Akaike, Takaaki, van der Vliet,

Journal:

Year:

2018

Language:

english

File:

PDF, 865 KB

english, 2018

22

The Reaction of Alkyl Hydropersulfides (RSSH, R = CH 3 and t Bu) with H 2 S in the Gas Phase and in Aqueous Solution

Zhang, Linxing, Zhang, Xinhao, Wu, Yun-Dong, Xie, Yaoming, Fukuto, Jon M, Schaefer, Henry F.

Journal:

Physical Chemistry Chemical Physics

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

23

Modulation of rat hepatic microsomal monooxygenase enzymes and cytotoxicity by diallyl sulfide

John F. Brady, Mong-Heng Wang, Jun-Yan Hong, Fang Xiao, Yan Li, Jeong-Sook H. Yoo, Shu M. Ning, Mao-Jung Lee, Jon M. Fukuto, Jeanne M. Gapac, Chung S. Yang

Journal:

Toxicology and Applied Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.21 MB

english, 1991

24

Nitric Oxide Inhibits Ornithine Decarboxylase by S-Nitrosylation

Philip M. Bauer, Jon M. Fukuto, Georgette M. Buga, Anthony E. Pegg, Louis J. Ignarro

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 61 KB

english, 1999

25

Chemical oxidation of N-hydroxyguanidine compounds: Release of nitric oxide, nitroxyl and possible relationship to the mechanism of biological nitric oxide generation

Jon M. Fukuto, Guillermo C. Wallace, Raina Hszieh, Gautam Chaudhuri

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 835 KB

english, 1992

26

Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles ||

Forman, Henry Jay, Fukuto, Jon, Torres, Martine

Year:

2004

Language:

english

File:

PDF, 9.98 MB

english, 2004

27

P019. Nitroxyl inactivates glutathione peroxidase and catalase, both purified and in cells, to prevent the catabolism of H2O2: Implications for peroxide based signaling

Matthew Irick Jackson, Jon M. Fukuto

Journal:

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

28

Production of reactive oxygen and nitrogen species by light irradiation of a nitrosyl phthalocyanine ruthenium complex as a strategy for cancer treatment

Heinrich, Tassiele A., Tedesco, Antonio Claudio, Fukuto, Jon M., da Silva, Roberto Santana

Journal:

Dalton Transactions

Year:

2014

Language:

english

File:

PDF, 714 KB

english, 2014

29

The Chemical Biology of Hydropersulfides and Related Species: Possible Roles in Cellular Protection and Redox Signaling

Alvarez, Lucia, Bianco, Christopher L, Toscano, John P, Lin, Joseph, Akaike, Takaaki, Fukuto, Jon

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 490 KB

english, 2017

30

The Chemistry and Biology of Nitroxyl (HNO): A Chemically Unique Species with Novel and Important Biological Activity

Jon M. Fukuto, Andrew S. Dutton, Kendall N. Houk

Journal:

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

31

Nitroxyl (HNO) signaling

Jon M. Fukuto, Christopher L. Bianco, Tyler A. Chavez

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

32

The pharmacology of nitroxyl (HNO) and its therapeutic potential: Not just the janus face of NO

Nazareno Paolocci, Matthew I. Jackson, Brenda E. Lopez, Katrina Miranda, Carlo G. Tocchetti, David A. Wink, Adrian J. Hobbs, Jon M. Fukuto

Journal:

Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 595 KB

english, 2007

33

N,O-Diacylated-N-hydroxyarylsulfonamides: Nitroxyl precursors with potent smooth muscle relaxant properties

Jon M. Fukuto, Raina Hszieh, Priya Gulati, Kenneth T. Chiang, Herbert T. Nagasawa

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 470 KB

english, 1992

34

Involvement of Reactive Persulfides in Biological Bismethylmercury Sulfide Formation

Abiko, Yumi, Yoshida, Eiko, Ishii, Isao, Fukuto, Jon M., Akaike, Takaaki, Kumagai, Yoshito

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

35

Gender Differences in Atherosclerosis

Hayashi, Toshio, Fukuto, Jon M., Ignarro, Louis J., Chaudhuri, Gautam

Journal:

Journal of Cardiovascular Pharmacology

Year:

1995

File:

PDF, 1000 KB

1995

36

1144-104 The novel organic nitroxyl donor, isopropylamine/nitric oxide exerts beta-independent positive inotropy/lusitropy in failing hearts

Tatsuo Katori, Carlo G Tocchetti, Katrina M Miranda, Hunter C Champion, Jon M Fukuto, David A Wink, David A Kass, Nazareno Paolocci

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 61 KB

english, 2004

37

Opposite Effects of Nitric Oxide and Nitroxyl on Postischemic Myocardial Injury

Xin L. Ma, Feng Gao, Gao-Lin Liu, Bernard L. Lopez, Theodore A. Christopher, Jon M. Fukuto, David A. Wink and Martin Feelisch

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.32 MB

english, 1999

38

Chronic Exposure of the RAW246.7 Macrophage Cell Line to H 2 O 2 Leads to Increased Catalase Expression

Goddu, Robert N., Henderson, Catherine F., Young, Amanda K., Muradian, Brooke E., Calderon, Leticia, Bleeg, Logan H., Fukuto, Jon M., Lin, Joseph

Journal:

Free Radical Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

39

Mechanisms of HNO biology

Journal:

Year:

2012

Language:

english

File:

PDF, 35 KB

english, 2012

40

P022. Synthesis, isolation, and characterization of nitroxyl anion

Christopher H. Switzer, Jon M. Fukuto, Patrick Farmer

Journal:

Year:

2006

Language:

english

File:

PDF, 46 KB

english, 2006

41

Transformation of dopamine and .alpha.-methyldopamine by NG108-15 cells: formation of thiol adducts

Patel, Nita, Kumagai, Yoshito, Unger, Steven E., Fukuto, Jon M., Cho, Arthur K.

Journal:

Chemical Research in Toxicology

Year:

1991

Language:

english

File:

PDF, 1.19 MB

english, 1991

42

Peracid oxidation of an N-hydroxyguanidine compound: a chemical model for the oxidation of N.omega.-hydroxy-L-arginine by nitric oxide synthase

Fukuto, Jon M., Stuehr, Dennis J., Feldman, Paul L., Bova, Michael P., Wong, Patrick

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 694 KB

english, 1993

43

Synthesis and bioactivity of N.omega.-hydroxyarginine: a possible intermediate in the biosynthesis of nitric oxide from arginine

Wallace, Guillermo C., Fukuto, Jon M.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 381 KB

english, 1991

44

Basal Release of Nitric Oxide from Aortic Rings is Greater in Female Rabbits than in Male Rabbits: Implications for Atherosclerosis

Toshio Hayashi, Jon M. Fukuto, Louis J. Ignarro and Gautam Chaudhuri

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.03 MB

english, 1992

45

An examination of quinone toxicity using the yeast Saccharomyces cerevisiae model system

Chester E Rodriguez, Masaru Shinyashiki, John Froines, Rong Chun Yu, Jon M Fukuto, Arthur K Cho

Journal:

Year:

2004

Language:

english

File:

PDF, 196 KB

english, 2004

46

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

Ono, Katsuhiko, Akaike, Takaaki, Sawa, Tomohiro, Kumagai, Yoshito, Wink, David A., Tantillo, Dean J., Hobbs, Adrian J., Nagy, Peter, Xian, Ming, Lin, Joseph, Fukuto, Jon M.

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 886 KB

english, 2014

47

Stereochemistry and mechanisms of reactions of electrophiles with organotin compounds

Fukuto, Jon M., Newman, David A., Jensen, Frederick R.

Journal:

Organometallics

Year:

1987

Language:

english

File:

PDF, 921 KB

english, 1987

48

Signaling and stress: The redox landscape in NOS2 biology

Thomas, Douglas D., Heinecke, Julie L., Ridnour, Lisa A., Cheng, Robert, Kesarwala, Aparna H., Switzer, Christopher H., McVicar, Daniel W., Roberts, David D., Glynn, Sharon, Fukuto, Jon M., Wink, Davi

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 3.23 MB

english, 2015

49

Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis

Hamid, Hisyam Abdul, Tanaka, Akira, Ida, Tomoaki, Nishimura, Akira, Matsunaga, Tetsuro, Fujii, Shigemoto, Morita, Masanobu, Sawa, Tomohiro, Fukuto, Jon M., Nagy, Péter, Tsutsumi, Ryouhei, Motohashi, H

Journal:

Year:

2019

Language:

english

File:

PDF, 404 KB

english, 2019

50

Mechanisms of HNO and NO Production from Angeli's Salt: Density Functional and CBS-QB3 Theory Predictions

Dutton, Andrew S., Fukuto, Jon M., Houk, K. N.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

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